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KMID : 0361720110220020081
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Korean Journal of perinatology
2011 Volume.22 No. 2 p.81 ~ p.87
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Preeclampsia and Innate Immunity
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Ahn Hyun-Kyong
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Abstract
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Preeclampsia(PE) remains a leading cause of maternal and fetal morbidity and mortality. Despite decades of intense research on the problem, there is no early pregnancy screening test to recognize those at risk. Recently, altered immune responses have been suspected to be involved in preeclampsia pathogenesis, which may concern the inflammatory context in which an immune response is mounted. In this review, the innate immunologic pathogenesis of the preeclampsia is reviewed.
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KEYWORD
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Immune response, Inflammation, Preeclampsia
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